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At this point, the effects of cold on the brain are most apparent. "At 18°C, we'll have a massive leak in our blood-brain barrier, and the brain is not protected anymore from the normal junk we produce," Gracheva said. The resulting flood of toxins through the hole-ridden ... Sign In | Popular Science. For a Limited Time: Get Headway Premium Lifetime Subscription at $49.97! Apps & Software. Backup & Storage. Business. Education. Leisure. Productivity. Security.... Sign in - BBC Science Focus Magazine AAAS Science | AAAS In the fourth century, the Greek mathematician Pappus of Alexandria praised bees for their "geometrical forethought." The hexagonal structure of their honeycomb seemed like the optimal way to partition two-dimensional space into cells of equal area and minimal perimeter — allowing the insects to cut down on how much wax they needed to produce, and to spend less time and energy building ... 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